This comprehensive assortment of 20 educational activities includes hands-on labs, interactive games, thought-provoking puzzles, and in-depth worksheets. They are each designed to provide students with a thorough understanding of the intricate processes involved in action potentials, neuron structure, and message transmission. Students will cultivate critical thinking, problem-solving, and collaboration skills while establishing a solid understanding of this tricky concept.
1. Action Potential Video

This engaging and thorough video focuses on the mechanism of action potentials, using clear and easy-to-understand language, animations, and diagrams to illustrate the concept. The review questions and interactive exercises can help reinforce learning while checking for student understanding.
Learn More: Khan Academy
2. Try a Word Search

Developing a basic vocabulary of impulse conduction along a neuron can help form a solid foundation for further learning. Apart from making the concepts more enjoyable and engaging, this word search turns complex scientific concepts into a game, thereby motivating student learning.
Learn More: Washington Education
3. Reinforce the Concept of Action Potentials With Flashcards

These online and printable flashcards simplify the subject matter into small, digestible pieces while supporting students in retaining the information more easily. They are a great tool for implementing spaced repetition, a learning technique that involves reviewing information at increasing intervals.
Learn More: Cram
4. Conduct an Experiment With a Giant Axon

In this action potential lab, students dissect a squid to expose the giant axon. They then connect electrodes to the axon and a device to record electrical activity. By stimulating the axon with small electrical pulses, they can observe and measure the action potential generated, learning about neuron communication and how changes in voltage trigger the signals that travel along the axon.
Learn More: Numerade
5. Conduct a Modeling Activity to Reinforce Fundamental Concepts

This hands-on activity involves building a physical simulation out of everyday classroom materials to help to visualize the process of action potentials. This can help them understand how voltage-gated ion channels open and close, and how the movement of ions across the cell membrane results in changes in the membrane potential.
Learn More: Teachers Pay Teachers
6. Sing a Song to Learn About Electrical Potential
This catchy song is designed to teach kids about action potentials in neurons. Incorporating key concepts of polarization and repolarisation can help students remember and understand the basic principles of neural communication.
Learn More: Neural Academy
7. Read A Book to Address Unanswered Questions

This best-selling classic provides an overview of the anatomy and physiology of the human brain as well as a clear explanation of the connection between action potentials and brain functions such as perception, learning, memory, and decision-making.
Learn More: Amazon
8. Try a Hands-On Neural Transmission Process Activity

After dividing students into three groups, assemble pool noodles with cups representing ion channels and paper plates for pumps. Have students at sodium channels push sodium ions through, and at potassium channels, have them push potassium ions out. Sodium-potassium pump teams consume a chocolate chip representing ATP to symbolize the transfer of ions.
Learn More: BioMed Heads
9. Compile A Giant Puzzle of a Motor Neuron

Coloring and assembling this giant printable neuron puzzle helps students visualize the structure and components of a neuron, making it easier to grasp the concept of impulse conduction. It’s also a great way to encourage collaboration while providing a multi-sensory learning opportunity.
Learn More: Better Lesson
10. Create a 3D Model of the Neuron

In this activity, students form teams to create labeled 3-D models of motor neurons using pipe cleaners, yarn, and pompoms. They research each neuron component, such as the cell body, dendrites, axon, and axon terminals, and incorporate this information into their models.
Learn More: BioMed Heads
11. Watch An Action Potential Animation
Have students watch this animated representation of how action potentials occur within neurons. This dynamic visual illustrates the stages of an action potential, including resting membrane potential, depolarization, repolarization, hyperpolarization, and the refractory period.
Learn More: Alila Medical Media
12. Solve a Crossword

This action potential crossword helps reinforce key vocabulary and concepts while engaging students in active problem-solving and enhancing critical thinking, pattern recognition, and logical reasoning skills.
Learn More: WordMint
13. View A Slideshow

This animated and colorful slideshow provides a clear overview of the nervous system, including action potentials, neuron structure, and neural communication, with intentional mistakes included. By spotting and correcting these mistakes, promoting critical thinking, and reinforcing their understanding of the subject.
Learn More: Twinkl
14. Try a Sequencing Activity

By arranging these sequencing cards in the correct order, students can learn about the neural communication process, including action potentials. Apart from encouraging collaboration, it’s a great way to assess student learning.
Learn More: Twinkl
15. Answer Comprehension Questions From a Reading

This clear and detailed reading passage guides students through the organization and function of the nervous system, including different types of neurons and their roles in transmitting messages in the human body. Why not combine it with a discussion to reinforce student comprehension?
Learn More: Education.com
16. Learn With Doodle Notes

These detailed doodle notes are a creative and visually appealing way to help students learn about action potentials and the nervous system. Having students create their own makes for an easy extension activity to test for understanding.
Learn More: Teachers Pay Teachers
17. Try a Quiz

In this interactive online game, students are presented with a diagram of a neuron during an action potential event and are challenged to correctly label various parts and stages involved in the process. Apart from providing immediate feedback, it offers an opportunity for self-paced learning.
Learn More: Purpose Games
18. Try a Hands-On Game

For this hands-on activity, students create a 3D model of a neuron using visually-appealing templates that can be printed and folded. It’s a great option for kinesthetic and visual learners that also encourages collaboration and active learning.
Learn More: Origami Organelles
19. Action Potential Game

This interactive, educational game features an underwater creature that reacts using water jets when its motor neurons are activated, helping to illustrate the role of action potential in living things.
Learn More: Crescent Loom
20. Solve An Online Action Potential Puzzle

This online jigsaw puzzle features an educational diagram illustrating the action potential process within a neuron. Players can choose their level of difficulty, from a simple 5×5 grid to more complex grids, and rearrange the jumbled pieces to form the complete diagram. Combining visual learning and problem-solving makes learning about this tricky concept both enjoyable and memorable.
Learn More: Puzzle Factory